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Visualizing Cancer Metabolism
We’ve been interested in cancer for some time. Unfortunately, it has taken a back seat to keeping the laboratory funded through our strengths in retinal circuitry and disease research. That said, we...
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Spinal Cord, And Science Left Behind
This is some data from a spinal cord project that we worked on some time ago, and an example of science that was left behind as we chased projects that would fund the lab. Most scientists have...
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Layers Upon Layers
A section of retina through the optic fiber layer, ganglion cell layer, inner plexiform layer, inner nuclear layer with amacrine and bipolar cells, the outer plexiform layer and the outer nuclear...
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Blood Vessels In The Eye
This is a flat mounted mouse eye, stained to show the blood vessels in it. It is absolutely remarkable that the closer you look, the more complexity and beauty there is in bioscience.
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Retinal Ganglion Cells
These colored spots represent retinal ganglion cells that have been processed with computational molecular phenotyping (CMP) to reveal the metabolic signals inside, then clustered based upon their...
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Glutamate In Plants
I’m reviewing a manuscript right now, and I always find it interesting that many neuroscientists seem to forget that the presence of small molecules like glutamate do not exclusively represent,...
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Season To Taste
This is tongue, that has been processed with computational molecular phenotyping (CMP) to reveal the metabolic signals inside the muscle and epithelial cells.
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Cone Photoreceptors
These are photoreceptors, processed with computational molecular phenotyping (CMP) to reveal the metabolic signals inside them for glutamate and a probe of activity, AGB.
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Retinal Tumor
This is a sampling of retinal tumor cells from a clonal population, that have been processed with computational molecular phenotyping (CMP) to reveal the metabolic signals inside them including...
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Photoreceptor Inner Segments
This image is a horizontal image through the inner segments of rod and cone photoreceptors in the mammalian retina, demonstrating the massive numbers of mitochondria, particularly the cone...
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Planet RP
Camera: Canon 1D Mk III Exposure: 1/15 Camera connected to an Olympus SZX16 Stereomicroscope. ISO: 400 This is a sample of human retina from a patient with retinitis pigmentosa. We could not do our...
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Retinal Waves
This is an image of degenerate retina, sectioned from the optic fiber layer, and into the remnant neural retina. This image has been processed with computational molecular phenotyping (CMP) to reveal...
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Dreaming I Am
The future is so hard to predict, much less engineer. This is true even if one thinks they have a relatively firm grasp on influencing outcomes. I have almost no time these days for scientific art...
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Neurogliovascular Connectomes
Neurogliovascular exploration is going to be a huge area of growth over the next while, and we’ve been developing our retinal connectomes in mouse, and non-human primate to take advantage of that...
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Metabolomic Retina In NYTimes
My Metabolomic Retina image is in a feature in the NYTimes with a print version of the article including a quote from me in the ScienceTimes section of the newspaper next Tuesday. It’s been fun seeing...
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